TY  - JOUR
T1  - Cross-generational effects of male reproductive success and offspring immunocompetence in Drosophila melanogaster
AU  - Guncay, Ashley
AU  - Balasubramaniam, Thiropa
AU  - Plagens, Katie
AU  - Weadge, Joel
AU  - Long, Tristan A.F.
Y1  - 2017/01/01
PY  - 2017
DA  - 2017/01/01
N1  - doi: 10.1139/facets-2015-0007
DO  - 10.1139/facets-2015-0007
T2  - FACETS
JF  - FACETS
SP  - 34
EP  - 52
VL  - 2
PB  - Canadian Science Publishing
N2  - In some species where males make no direct contribution to a female?s lifetime reproductive success, females choose mates based on the indirect benefits manifested in their offspring. One trait that may be subject to this sexual selection is immunocompetence (the ability to mount an immune response following exposure to pathogens); however, the results of previous work on its link to male attractiveness have been ambiguous. Herein we examine the life history consequences of mating with males with a history of failure or success in reproductive competitions in Drosophila melanogaster. By examining egg-to-adult survival, body weights, and bacterial loads of offspring reared in either the absence or presence of a bacterial pathogen, we were able to examine whether sire reproductive success was associated with their offsprings? ability to respond to an immunological challenge and other life history traits. Our results are partially consistent with the predictions of the ?immunocompetence handicap hypothesis?: competitively successful males (?studs?) sire male offspring that are better able to handle an immunological challenge than those sired by competitively unsuccessful males (?duds?). However, our assay also revealed the opposite pattern in female offspring, suggestive of the complicating presence of alleles with sexually antagonistic effects on the expression of this important life history trait.
AB  - In some species where males make no direct contribution to a female?s lifetime reproductive success, females choose mates based on the indirect benefits manifested in their offspring. One trait that may be subject to this sexual selection is immunocompetence (the ability to mount an immune response following exposure to pathogens); however, the results of previous work on its link to male attractiveness have been ambiguous. Herein we examine the life history consequences of mating with males with a history of failure or success in reproductive competitions in Drosophila melanogaster. By examining egg-to-adult survival, body weights, and bacterial loads of offspring reared in either the absence or presence of a bacterial pathogen, we were able to examine whether sire reproductive success was associated with their offsprings? ability to respond to an immunological challenge and other life history traits. Our results are partially consistent with the predictions of the ?immunocompetence handicap hypothesis?: competitively successful males (?studs?) sire male offspring that are better able to handle an immunological challenge than those sired by competitively unsuccessful males (?duds?). However, our assay also revealed the opposite pattern in female offspring, suggestive of the complicating presence of alleles with sexually antagonistic effects on the expression of this important life history trait.
M3  - doi: 10.1139/facets-2015-0007
UR  - https://doi.org/10.1139/facets-2015-0007
Y2  - 2024/04/23
ER  - 


TY  - BOOK
AU  - Andersson, M
TI  - Sexual selection
Y1  - 1994
ED  - 1st edition
ER  - 

TY  - JOUR
T1  - Drosophila melanogaster as a model host for studying Pseudomonas aeruginosa infection
AU  - Apidianakis, Y
AU  - Rahme, LG
JO  - Nature Protocols
Y1  - 2009
VL  - 4
SP  - 1285
ER  - 

TY  - BOOK
AU  - Arnqvist, G
AU  - Rowe, L
TI  - Sexual conflict
Y1  - 2005
ER  - 

TY  - BOOK
AU  - Ashburner, M
TI  - Drosophila: a laboratory handbook
Y1  - 1989
ER  - 

TY  - JOUR
T1  - Inducible antibacterial defence system in Drosophila
AU  - Boman, HG
AU  - Nilsson, I
AU  - Rasmuson, B
JO  - Nature
Y1  - 1972
VL  - 237
SP  - 232
ER  - 

TY  - BOOK
AU  - Broderick, NA
AU  - Lemaitre, B
AU  - Rolff, J
AU  - Reynolds, S
TI  - Insect infection and immunity: evolution, ecology, and mechanisms
Y1  - 2009
SP  - 13
ER  - 

TY  - JOUR
T1  - Bacterial communities of diverse Drosophila species: ecological context of a host–microbe model system
AU  - Chandler, JA
AU  - Lang, JM
AU  - Bhatnagar, S
AU  - Eisen, JA
AU  - Kopp, A
JO  - PLoS Genetics
Y1  - 2011
VL  - 7
SP  - e1002272
ER  - 

TY  - JOUR
T1  - A cost of mating with males that do not transfer sperm in female Drosophila melanogaster
AU  - Chapman, T
JO  - Journal of Insect Physiology
Y1  - 1992
VL  - 38
SP  - 223
ER  - 

TY  - JOUR
T1  - Seminal fluid‐mediated fitness traits in Drosophila
AU  - Chapman, T
JO  - Heredity
Y1  - 2001
VL  - 87
SP  - 511
ER  - 

TY  - JOUR
T1  - Experimental evolution of accelerated development in Drosophila. 1. Developmental speed and larval survival
AU  - Chippindale, AK
AU  - Alipaz, JA
AU  - Chen, HW
AU  - Rose, MR
JO  - Evolution
Y1  - 1997
VL  - 51
SP  - 1536
ER  - 

TY  - BOOK
AU  - Cohen, J
TI  - Statistical power analysis for the behavioral sciences
Y1  - 1988
ED  - 2nd edition
ER  - 

TY  - JOUR
T1  - Drosophila as a model host for Pseudomonas aeruginosa infection
AU  - D’Argenio, DA
AU  - Gallagher, LA
AU  - Berg, CA
AU  - Manoil, C
JO  - Journal of Bacteriology
Y1  - 2001
VL  - 183
SP  - 1466
ER  - 

TY  - BOOK
AU  - Darwin, C
TI  - The descent of man, and selection in relation to sex
Y1  - 1871
ER  - 

TY  - JOUR
T1  - Female mating bias results in conflicting sex-specific offspring fitness
AU  - Fedorka, KM
AU  - Mousseau, TA
JO  - Nature
Y1  - 2004
VL  - 429
SP  - 65
ER  - 

TY  - JOUR
T1  - Association between feeding rate and parasitoid resistance in Drosophila melanogaster
AU  - Fellowes, MDE
AU  - Kraaijeveld, AR
AU  - Godfray, HCJ
JO  - Evolution
Y1  - 1999
VL  - 53
SP  - 1302
ER  - 

TY  - JOUR
T1  - Parasites, bright males, and the immunocompetence handicap
AU  - Folstad, I
AU  - Karter, AJ
JO  - American Naturalist
Y1  - 1992
VL  - 139
SP  - 603
ER  - 

TY  - JOUR
T1  - Courtship in Drosophila
AU  - Greenspan, RJ
AU  - Ferveur, J-F
JO  - Annual Review of Genetics
Y1  - 2000
VL  - 34
SP  - 205
ER  - 

TY  - JOUR
T1  - The mating of a fly
AU  - Hall, JC
JO  - Science
Y1  - 1994
VL  - 264
SP  - 1702
ER  - 

TY  - JOUR
T1  - Heritable true fitness and bright birds: a role for parasites?
AU  - Hamilton, WD
AU  - Zuk, M
JO  - Science
Y1  - 1982
VL  - 218
SP  - 384
ER  - 

TY  - JOUR
T1  - Effects of the male accessory gland secretion on oviposition and remating in females of Drosophila melanogaster
AU  - Hihara, F
JO  - Zoological Magazine
Y1  - 1981
VL  - 90
SP  - 307
ER  - 

TY  - JOUR
T1  - The immune response of Drosophila
AU  - Hoffmann, JA
JO  - Nature
Y1  - 2003
VL  - 426
SP  - 33
ER  - 

TY  - JOUR
T1  - Perspective: chase-away sexual selection: antagonistic seduction versus resistance
AU  - Holland, B
AU  - Rice, WR
JO  - Evolution
Y1  - 1998
VL  - 52
SP  - 1
ER  - 

TY  - JOUR
T1  - Sex and death: microevolutionary trade-offs between reproductive and immune investment in dung flies
AU  - Hosken, DJ
JO  - Current Biology
Y1  - 2001
VL  - 11
SP  - R379
ER  - 

TY  - JOUR
T1  - Genetic covariance of fitness correlates: what genetic correlations are made of and why it matters
AU  - Houle, D
JO  - Evolution
Y1  - 1991
VL  - 45
SP  - 630
ER  - 

TY  - JOUR
T1  - Proteins of the Drosophila melanogaster male reproductive system: two-dimensional gel patterns of proteins synthesized in the XO, XY, and XYY testis and paragonial gland and evidence that the Y chromosome does not code for structural sperm proteins
AU  - Ingman-Baker, J
AU  - Candido, EPM
JO  - Biochemical Genetics
Y1  - 1980
VL  - 18
SP  - 809
ER  - 

TY  - JOUR
T1  - Twin intromittent organs of Drosophila for traumatic insemination
AU  - Kamimura, Y
JO  - Biology Letters
Y1  - 2007
VL  - 3
SP  - 401
ER  - 

TY  - JOUR
T1  - Genes that fight infection: what the Drosophila genome says about animal immunity
AU  - Khush, RS
AU  - Lemaitre, B
JO  - Trends in Genetics
Y1  - 2000
VL  - 16
SP  - 442
ER  - 

TY  - JOUR
T1  - The evolution of mating preferences and the paradox of the lek
AU  - Kirkpatrick, M
AU  - Ryan, MJ
JO  - Nature
Y1  - 1991
VL  - 350
SP  - 33
ER  - 

TY  - JOUR
T1  - Sexually transmitted diseases of insects: distribution, evolution, ecology and host behavior
AU  - Knell, RJ
AU  - Webberley, KM
JO  - Biological Reviews
Y1  - 2004
VL  - 79
SP  - 557
ER  - 

TY  - JOUR
T1  - Unifying and testing models of sexual selection
AU  - Kokko, H
AU  - Jennions, MD
AU  - Brooks, R
JO  - Annual Review of Ecology, Evolution, and Systematics
Y1  - 2006
VL  - 37
SP  - 43
ER  - 

TY  - JOUR
T1  - Males influence maternal effects that promote sexual selection: a quantitative genetic experiment with dung beetles Onthophagus taurus
AU  - Kotiaho, JS
AU  - Simmons, LW
AU  - Hunt, J
AU  - Tomkins, JL
JO  - American Naturalist
Y1  - 2003
VL  - 161
SP  - 852
ER  - 

TY  - JOUR
T1  - Trade-off between parasitoid resistance and larval competitive ability in Drosophila melanogaster
AU  - Kraaijeveld, AR
AU  - Godfray, HCJ
JO  - Nature
Y1  - 1997
VL  - 389
SP  - 278
ER  - 

TY  - BOOK
AU  - Kraaijeveld, AR
AU  - Wertheim, B
AU  - Rolff, J
AU  - Reynolds, S
TI  - Insect infection and immunity: evolution, ecology, and mechanisms
Y1  - 2009
SP  - 187
ER  - 

TY  - JOUR
T1  - The cost of mating rises nonlinearly with copulation frequency in a laboratory population of Drosophila melanogaster
AU  - Kuijper, B
AU  - Stewart, AD
AU  - Rice, WR
JO  - Journal of Evolutionary Biology
Y1  - 2006
VL  - 19
SP  - 1795
ER  - 

TY  - JOUR
T1  - Mating and immunity in invertebrates
AU  - Lawniczak, MK
AU  - Barnes, AI
AU  - Linklater, JR
AU  - Boone, JM
AU  - Wigby, S
AU  - Chapman, T
JO  - Trends in Ecology & Evolution
Y1  - 2007
VL  - 22
SP  - 48
ER  - 

TY  - JOUR
T1  - The influence of male and female body size on copulation duration and fecundity in Drosophila melanogaster
AU  - Lefranc, A
AU  - Bundgaard, J
JO  - Hereditas
Y1  - 2000
VL  - 132
SP  - 243
ER  - 

TY  - JOUR
T1  - Quantifying the gender load: can population crosses reveal interlocus sexual conflict?
AU  - Long, TAF
AU  - Montgomerie, R
AU  - Chippindale, AK
JO  - Philosophical Transactions of the Royal Society of London Series B
Y1  - 2006
VL  - 361
SP  - 363
ER  - 

TY  - JOUR
T1  - The timing of mating influences reproductive success in Drosophila melanogaster: implications for sexual conflict
AU  - Long, TAF
AU  - Pischedda, A
AU  - Nichols, RV
AU  - Rice, WR
JO  - Journal of Evolutionary Biology
Y1  - 2010
VL  - 23
SP  - 1024
ER  - 

TY  - JOUR
T1  - A cost of sexual attractiveness to high-fitness females
AU  - Long, TAF
AU  - Pischedda, A
AU  - Stewart, AD
AU  - Rice, WR
JO  - PLoS Biology
Y1  - 2009
VL  - 7
SP  - e1000254
ER  - 

TY  - JOUR
T1  - Male mating experience and competitive courtship success in Drosophila melanogaster
AU  - Markow, TA
AU  - Quaid, M
AU  - Kerr, S
JO  - Nature
Y1  - 1978
VL  - 276
SP  - 821
ER  - 

TY  - JOUR
T1  - Sexual selection and immune function in Drosophila melanogaster
AU  - McKean, KA
AU  - Nunney, L
JO  - Evolution
Y1  - 2008
VL  - 62
SP  - 386
ER  - 

TY  - JOUR
T1  - Sick of mating: sexual transmission of a pathogenic bacterium in Drosophila melanogaster
AU  - Miest, TS
AU  - Bloch-Qazi, MC
JO  - Fly
Y1  - 2008
VL  - 2
SP  - 215
ER  - 

TY  - JOUR
T1  - A possible tradeoff between developmental rate and pathogen resistance in Drosophila melanogaster
AU  - Modak, SG
AU  - Satish, KM
AU  - Mohan, J
AU  - Dey, S
AU  - Raghavendra, N
AU  - Shakarad, M
JO  - Journal of Genetics
Y1  - 2009
VL  - 88
SP  - 253
ER  - 

TY  - JOUR
T1  - An ectopic expression screen reveals the protective and toxic effects of Drosophila seminal fluid proteins
AU  - Mueller, JL
AU  - Page, JL
AU  - Wolfner, MF
JO  - Genetics
Y1  - 2007
VL  - 175
SP  - 777
ER  - 

TY  - JOUR
T1  - On sexual dimorphism in immune function
AU  - Nunn, CL
AU  - Lindenfors, P
AU  - Pursall, ER
AU  - Rolff, J
JO  - Philosophical Transactions of the Royal Society of London Series B
Y1  - 2009
VL  - 364
SP  - 61
ER  - 

TY  - JOUR
T1  - Conflict between direct and indirect benefits of female choice in desert Drosophila
AU  - Oneal, E
AU  - Connallon, T
AU  - Knowles, LL
JO  - Biology Letters
Y1  - 2007
VL  - 3
SP  - 29
ER  - 

TY  - JOUR
T1  - Male size and mating success in Drosophila melanogaster and D. pseudoobscura under field conditions
AU  - Partridge, L
AU  - Hoffmann, A
AU  - Jones, JS
JO  - Animal Behaviour
Y1  - 1987
VL  - 35
SP  - 468
ER  - 

TY  - JOUR
T1  - Drosophila sex-peptide stimulates female innate immune system after mating via the Toll and Imd pathways
AU  - Peng, J
AU  - Zipperlen, P
AU  - Kubli, E
JO  - Current Biology
Y1  - 2005
VL  - 15
SP  - 1690
ER  - 

TY  - JOUR
T1  - The ontogeny and evolution of sex-biased gene expression in Drosophila melanogaster
AU  - Perry, JC
AU  - Harrison, PW
AU  - Mank, JE
JO  - Molecular Biology and Evolution
Y1  - 2014
VL  - 31
SP  - 1206
ER  - 

TY  - JOUR
T1  - Intralocus sexual conflict diminishes the benefits of sexual selection
AU  - Pischedda, A
AU  - Chippindale, AK
JO  - PLoS Biology
Y1  - 2006
VL  - 4
SP  - e356
ER  - 

TY  - JOUR
T1  - Testing the genetics underlying the co-evolution of mate choice and ornament in the wild
AU  - Qvarnström, A
AU  - Brommer, JE
AU  - Gustafsson, L
JO  - Nature
Y1  - 2006
VL  - 441
SP  - 84
ER  - 

TY  - BOOK
AU  - Rice, WR
AU  - Chippindale, AK
AU  - Etges, WJ
AU  - Noor, MA
TI  - Genetics of mate choice: from sexual selection to sexual isolation
Y1  - 2002
SP  - 179
ER  - 

TY  - JOUR
T1  - Bateman’s principle and immunity
AU  - Rolff, J
JO  - Proceedings of the Royal Society of London Series B
Y1  - 2002
VL  - 269
SP  - 867
ER  - 

TY  - JOUR
T1  - Selection for parasitoid resistance alters mating success in Drosophila
AU  - Rolff, J
AU  - Kraaijeveld, AR
JO  - Proceedings of the Royal Society of London Series B
Y1  - 2003
VL  - 270
IS  - 2
SP  - S154
ER  - 

TY  - JOUR
T1  - Invertebrate ecological immunology
AU  - Rolff, J
AU  - Siva-Jothy, MT
JO  - Science
Y1  - 2003
VL  - 301
SP  - 472
ER  - 

TY  - JOUR
T1  - Genetic constraints and sexual dimorphism in immune defense
AU  - Rolff, J
AU  - Armitage, SAO
AU  - Coltman, DW
JO  - Evolution
Y1  - 2005
VL  - 59
SP  - 1844
ER  - 

TY  - JOUR
T1  - Laboratory evolution of postponed senescence in Drosophila melanogaster
AU  - Rose, MR
JO  - Evolution
Y1  - 1984
VL  - 38
SP  - 1004
ER  - 

TY  - JOUR
T1  - The lek paradox and the capture of genetic variance by condition dependent traits
AU  - Rowe, L
AU  - Houle, D
JO  - Proceedings of the Royal Society of London Series B
Y1  - 1996
VL  - 263
SP  - 1415
ER  - 

TY  - JOUR
T1  - An experimental test for indirect benefits in Drosophila melanogaster
AU  - Rundle, HD
AU  - Ödeen, A
AU  - Mooers, AØ
JO  - BMC Evolutionary Biology
Y1  - 2007
VL  - 7
SP  - 36
ER  - 

TY  - BOOK
AU  - Ryan, KJ
AU  - Ray, CG
TI  - Medical microbiology
Y1  - 1994
ER  - 

TY  - JOUR
T1  - Ecological immunology: costly parasite defences and trade-offs in evolutionary ecology
AU  - Sheldon, BC
AU  - Verhulst, S
JO  - Trends in Ecology & Evolution
Y1  - 1996
VL  - 11
SP  - 317
ER  - 

TY  - JOUR
T1  - Seminal fluid protein depletion and replenishment in the fruit fly, Drosophila melanogaster: an ELISA-based method for tracking individual ejaculates
AU  - Sirot, LK
AU  - Buehner, NA
AU  - Fiumera, AC
AU  - Wolfner, MF
JO  - Behavioral Ecology and Sociobiology
Y1  - 2009
VL  - 63
SP  - 1505
ER  - 

TY  - JOUR
T1  - Host species and environmental effects on bacterial communities associated with Drosophila in the laboratory and in the natural environment
AU  - Staubach, F
AU  - Baines, JF
AU  - Künzel, S
AU  - Bik, EM
AU  - Petrov, DA
JO  - PLoS ONE
Y1  - 2013
VL  - 8
SP  - e70749
ER  - 

TY  - BOOK
AU  - Sullivan, W
AU  - Ashburner, M
AU  - Hawley, RS
TI  - Drosophila protocols
Y1  - 2000
ER  - 

TY  - BOOK
AU  - Trivers, RL
AU  - Campbell, B
TI  - Sexual selection and the descent of man 1871–1971
Y1  - 1972
SP  - 136
ER  - 

TY  - JOUR
T1  - Rapid loss of behavioral plasticity and immunocompetence under intense sexual selection
AU  - van Lieshout, E
AU  - McNamara, KB
AU  - Simmons, LW
JO  - Evolution
Y1  - 2014
VL  - 68
SP  - 2550
ER  - 

TY  - JOUR
T1  - Acquisition and allocation of resources: their influence on variation in life history tactics
AU  - van Noordwijk, AJ
AU  - de Jong, G
JO  - The American Naturalist
Y1  - 1986
VL  - 128
SP  - 137
ER  - 

TY  - JOUR
T1  - Sex-biased immunity is driven by relative differences in reproductive investment
AU  - Vincent, CM
AU  - Gwynne, DT
JO  - Proceedings of the Royal Society of London B: Biological Sciences
Y1  - 2014
VL  - 281
SP  - 20140333
ER  - 

TY  - JOUR
T1  - Sexual antagonism for resistance and tolerance to infection in Drosophila melanogaster
AU  - Vincent, CM
AU  - Sharp, NP
JO  - Proceedings of the Royal Society of London Series B
Y1  - 2014
VL  - 281
SP  - 20140987
ER  - 

TY  - JOUR
T1  - Alternative hypotheses linking the immune system and mate choice for good genes
AU  - Westneat, DF
AU  - Birkhead, TR
JO  - Proceedings of the Royal Society of London Series B
Y1  - 1998
VL  - 265
SP  - 1065
ER  - 

TY  - JOUR
T1  - The effect of pathogens on selection against deleterious mutations in Drosophila melanogaster
AU  - Young, JA
AU  - Yourth, CP
AU  - Agrawal, AF
JO  - Journal of Evolutionary Biology
Y1  - 2009
VL  - 22
SP  - 2125
ER  - 

TY  - JOUR
T1  - Mate selection—a selection for a handicap
AU  - Zahavi, A
JO  - Journal of Theoretical Biology
Y1  - 1975
VL  - 53
SP  - 205
ER  - 

TY  - BOOK
AU  - Zera, AJ
AU  - Harshman, LG
AU  - Garland, T
AU  - Rose, MR
TI  - Experimental evolution: concepts, methods, and applications
Y1  - 2009
SP  - 217
ER  - 

TY  - JOUR
T1  - Reproductive strategies and disease susceptibility: an evolutionary viewpoint
AU  - Zuk, M
JO  - Parasitology Today
Y1  - 1990
VL  - 6
IS  - 7
SP  - 231
ER  -